Status:

COMPLETED

Steroid Profiles in PCOS and Effect of OCP Treatment

Lead Sponsor:

Istanbul University

Conditions:

Polycystic Ovary Syndrome (PCOS)

Eligibility:

FEMALE

13-21 years

Brief Summary

This prospective observational study investigates the changes in serum steroid intermediates assessed by liquid chromatography-mass spectrometry (LC-MS/MS) in adolescents and young women with polycyst...

Detailed Description

The study enrolled 56 female patients aged 13-21 years with a diagnosis of PCOS according to Rotterdam criteria. At baseline, all participants underwent LC-MS/MS steroid profiling. A subgroup of 15 pa...

Eligibility Criteria

Inclusion

  • Diagnosis of PCOS based on Rotterdam criteria
  • Age between 13 and 21 years
  • No hormonal treatment in the 3 months prior to study enrollment
  • Consent provided

Exclusion

  • Congenital adrenal hyperplasia
  • Cushing's syndrome
  • Pregnancy
  • Use of hormonal medications within 1 year prior to baseline

Key Trial Info

Start Date :

January 2 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 4 2025

Estimated Enrollment :

56 Patients enrolled

Trial Details

Trial ID

NCT07161440

Start Date

January 2 2021

End Date

August 4 2025

Last Update

September 8 2025

Active Locations (1)

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Istanbul University

Istanbul, Turkey (Türkiye), 34093