Status:

RECRUITING

Step Count and Treatment Response in Neoadjuvant Breast Cancer

Lead Sponsor:

Ankara Etlik City Hospital

Conditions:

Breast Neoplasm Malignant Female

Exercise

Eligibility:

FEMALE

18+ years

Brief Summary

This prospective multicenter observational study (NEOBRE-STEP) investigates the impact of daily step counts, measured by Huawei Fit 2 smartwatches, on treatment response in patients with non-metastati...

Detailed Description

Physical activity and sleep quality are important prognostic factors in oncology, but objective and continuous monitoring during neoadjuvant systemic therapy is limited. Wearable devices provide non-i...

Eligibility Criteria

Inclusion

  • Female patients aged ≥18 years.
  • Pathologically confirmed non-metastatic HER2-negative breast cancer.
  • Candidates scheduled to receive neoadjuvant systemic therapy followed by surgery.
  • ECOG performance status 0-2.
  • Ability to provide informed consent.

Exclusion

  • Metastatic breast cancer at diagnosis.
  • HER2-positive breast cancer.
  • Previous systemic therapy for current breast cancer.
  • Severe comorbidities limiting mobility or physical activity (e.g., advanced neurologic or musculoskeletal disorders).
  • ECOG performance status ≥3.
  • Pregnancy or breastfeeding.
  • Refusal or inability to use a smartwatch device.

Key Trial Info

Start Date :

September 8 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 29 2026

Estimated Enrollment :

82 Patients enrolled

Trial Details

Trial ID

NCT07162675

Start Date

September 8 2025

End Date

March 29 2026

Last Update

September 12 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Etlik City Hospital, Medical Oncology Department

Ankara, Yenimahalle, Turkey (Türkiye), 06210

2

Gazi University Medical Oncology Department

Ankara, Çankaya, Turkey (Türkiye)