Status:
COMPLETED
Guiding Fluid Resuscitation in Septic Shock: Ultrasound vs. Noninvasive Cardiac Output Monitoring
Lead Sponsor:
Mai Xiaowei
Collaborating Sponsors:
Guangzhou Panyu Central Hospital
Conditions:
Septic Shock
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This randomized controlled study investigates the value of critical care ultrasound and non-invasive cardiac output monitoring in guiding fluid resuscitation for patients with septic shock in the emer...
Detailed Description
This study is a prospective randomized controlled trial conducted in the Emergency Department of Guangzhou Panyu Central Hospital. Eligible adult patients with septic shock, admitted between july 2023...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- diagnosis of septic shock in accordance with the Surviving Sepsis Campaign International ;
- receipt of initial fluid resuscitation in the emergency department with a hospital stay of at least 6 hours;
- age ≥ 18 years;
- provision of informed consent.
- Excluded criteria:
- contraindications to rapid fluid administration (e.g., end-stage renal disease, end-stage heart failure, acute pulmonary edema);
- inability to comply with treatment, such as patients with severe trauma, burns, cancer undergoing chemotherapy, pregnant or lactating women, and those with mental illness;
- withdrawal from treatment or transfer to another facility within 24 hours of admission.
Exclusion
Key Trial Info
Start Date :
July 5 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 31 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT07162857
Start Date
July 5 2023
End Date
July 31 2025
Last Update
September 22 2025
Active Locations (1)
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1
Panyu Central Hospital Affiliated to Guangzhou Medical University
Guangzhou, Guangdong, China, 510000