Status:
COMPLETED
Litholytic Therapy for Coral Urate Nephrolithiasis
Lead Sponsor:
Moscow State University of Medicine and Dentistry
Conditions:
Urolithiasis
Eligibility:
All Genders
Phase:
NA
Brief Summary
This is a prospective cohort study, patients with coralloid nephrolithiasis. Purpose of the study: to evaluate the efficacy and safety of litholytic therapy of coral-like urate nephrolithiasis with ci...
Detailed Description
Anthropometric parameters height and weight were recorded in all patients, body mass index was calculated. All patients underwent MSCT of the urinary tract to assess the volume of density and concreme...
Eligibility Criteria
Inclusion
- Coral-shaped calculus, which fills one or more calyx and pelvis (K2-K4 according to the classification of coral-shaped concretions);
- The urate composition of the kidney stone was confirmed using dual-energy MSCT;
- Unimpaired or restored (by draining the kidney) urine outflow from the kidney;
- Persistently acidic urine pH (pH 5.8 or less);
- Stone density is 550 Hounsfield units or less;
- Informed voluntary consent of the patient to participate in the study;
- Patient's readiness for conservative treatment;
- No contraindications to therapy with citrate mixtures;
Exclusion
Key Trial Info
Start Date :
January 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 9 2025
Estimated Enrollment :
49 Patients enrolled
Trial Details
Trial ID
NCT07162974
Start Date
January 1 2023
End Date
January 9 2025
Last Update
September 9 2025
Active Locations (1)
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1
Moscow state university of medicine and dentistry named after A.I. Evdokimov
Moscow, Russia, 127473