Status:

RECRUITING

Effect of Probiotic Intervention on Travel-Related Health Conditions During Short-Term Overseas Travel

Lead Sponsor:

Universiti Sains Malaysia

Collaborating Sponsors:

Tsinghua University Science and Technology

Conditions:

Healthy Adults

Eligibility:

All Genders

18-65 years

Phase:

PHASE2

Brief Summary

International travel disrupts gut health through dietary changes, microbial exposure, and stress, often causing gastrointestinal symptoms like traveler's diarrhea and sleep disturbances. These shifts ...

Detailed Description

International travel exposes individuals to abrupt changes in diet, water sources, microbial exposures, sleep schedules, and psychological stress. These factors often perturb the gut microbiota and in...

Eligibility Criteria

Inclusion

  • Generally healthy adults
  • Scheduled to undertake a short-term round trip (less than 7 days) to abroad
  • Able to complete study procedures
  • Willing to take intervention products

Exclusion

  • Use of antibiotics, probiotics, hormones, immunosuppressants, biologics or JAK inhibitors within four weeks prior to study
  • Chronic or severe systemic diseases (including cardiovascular, hepatic, renal, malignant or psychiatric disorders)
  • Uncontrolled parasitic infections
  • Long-term use of corticosteroids, growth hormone, vitamin B12, lysine or inositol
  • Major surgery within one month
  • Allergy to probiotic components
  • Other conditions deemed inappropriate by investigators

Key Trial Info

Start Date :

July 31 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

46 Patients enrolled

Trial Details

Trial ID

NCT07163819

Start Date

July 31 2025

End Date

December 31 2025

Last Update

September 17 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Tsinghua University Science and Technology

Haidian, Beijing Municipality, China, 100080

2

Universiti Sains Malaysia

George Town, Pulau Pinang, Malaysia, 11800