Status:
NOT_YET_RECRUITING
Efficacy of Topical Atropine Eye Drops for Control of Myopia Progression Among Children Attending Mansoura University Ophthalmic Center
Lead Sponsor:
Mansoura University
Conditions:
Myopia
Eligibility:
All Genders
3-18 years
Phase:
PHASE2
PHASE3
Brief Summary
This randomized controlled trial aims to evaluate the efficacy and safety of low-dose topical atropine sulphate (0.05%), a non-selective muscarinic antagonist, in slowing the progression of myopia and...
Eligibility Criteria
Inclusion
- Myopia of at least -1.0 D in both eyes, astigmatism of less than 2.0 D, anisometropia of objective spherical equivalent ≤ 1.50 D.
- Documented myopic progression of at least 0.5 D in the past one year.
Exclusion
- Children with ocular or systemic diseases that potentially influence myopia or refractive power.
- Ocular diseases, e.g., cataracts, glaucoma
- Posterior segment hereditary and acquired pathological disorders.
- History of any previous ocular surgery.
- History of any ocular injuries.
- Previous use of interventions (such as atropine, pirenzepine, orthokeratology lens, or other optical methods) for myopia control
- Allergy to atropine, cyclopentolate or benzalkonium chloride
Key Trial Info
Start Date :
September 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2027
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT07164092
Start Date
September 1 2025
End Date
September 1 2027
Last Update
September 9 2025
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