Status:

NOT_YET_RECRUITING

Postprandial Distress Itopride Cohort Trial

Lead Sponsor:

Universitaire Ziekenhuizen KU Leuven

Conditions:

Postprandial Distress Syndrome

Functional Dyspepsia

Eligibility:

All Genders

18+ years

Brief Summary

Functional Dyspepsia (FD) is a common gastrointestinal disorder affecting about 7.2% of the population, characterized by gastroduodenal symptoms without an identifiable organic cause. It is divided in...

Eligibility Criteria

Inclusion

  • Patient diagnosed with functional dyspepsia as per physician clinical criteria
  • Patient must sign an informed consent document before the initiation of any study-related procedures indicating that he or she understands the purpose and procedures required for the study and is willing to participate in the study.
  • Patient must speak Dutch or French

Exclusion

  • Patient with other clinical diagnosis than functional dyspepsia that can explain their gastrointestinal symptoms.
  • Patient has any of the following surgical history:
  • Any abdominal surgery within the 3 months prior to screening;
  • Subject has a history of major gastric, hepatic, pancreatic, or intestinal surgery (appendectomy, hemorrhoidectomy, cholecystectomy, or polypectomy more than 3 months earlier are allowed).
  • Patient has an unstable cardiac, pulmonary, renal, hepatic, metabolic, or hematologic condition.
  • Patient has a history of active malignancy within 3 years before screening (except squamous and basal cell carcinomas and cervical carcinoma in situ).
  • Patient has received an investigational drug or used an investigational medical device within 30 days prior to randomization, or is currently enrolled in an investigational study.
  • In case of psychotropic drug use: patient NOT on stable doses of antidepressants (i.e., for the 3 months prior to pre-screening) will not be allowed to participate in the study. Habitual use of benzodiazepines is permitted.
  • Patient is pregnant or breastfeeding.
  • Patient has any condition that, in the opinion of the investigator, would compromise the well-being of the patient or the study or prevent the patient from meeting or performing study requirements.

Key Trial Info

Start Date :

October 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 31 2026

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT07165301

Start Date

October 1 2025

End Date

July 31 2026

Last Update

September 10 2025

Active Locations (1)

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1

UZ Leuven

Leuven, Belgium, 3000