Status:

NOT_YET_RECRUITING

Effect of Product Characteristics on the Abuse Liability of Nicotine Pouches

Lead Sponsor:

Emory University

Collaborating Sponsors:

National Institute on Drug Abuse (NIDA)

Conditions:

Nicotine Addiction

Eligibility:

All Genders

21-35 years

Phase:

NA

Brief Summary

The goal of this study is to assess the effects of nicotine concentration and its interplay with pH on sensory experience, product appeal, and abuse liability of NPs among young adults NP users. Prim...

Detailed Description

Oral nicotine pouches (NPs) are a rapidly growing segment of nicotine products regulated by the U.S. Food and Drug Administration (FDA). These microfiber pouches contain nicotine but no tobacco leaf, ...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Current established users of nicotine pouches (have used nicotine pouches in the past 30 days \& currently use nicotine pouches every day or someday)
  • Positive cotinine test via saliva test strip
  • Those who are unmotivated to quit nicotine use
  • Read and speak English.
  • Poly-users of nicotine pouches, e-cigarettes (e.g., vape ≥20 days/month), and tobacco (e.g., ≥4 cigarettes/day for ≥2 years) will be eligible for participation
  • Exclusion Criteria
  • Planning to cut down or quit using nicotine in the next 30 days
  • Currently pregnant or breastfeeding
  • History of stroke, seizures, high blood pressure, heart disease/problems, or cardiovascular disease contraindications for nicotine.

Exclusion

    Key Trial Info

    Start Date :

    January 1 2026

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    January 1 2028

    Estimated Enrollment :

    84 Patients enrolled

    Trial Details

    Trial ID

    NCT07165808

    Start Date

    January 1 2026

    End Date

    January 1 2028

    Last Update

    November 24 2025

    Active Locations (1)

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    Rollins School of Public Health

    Atlanta, Georgia, United States, 30322