Status:
RECRUITING
The Effect of Mobilization on Inflammatory Biomarkers in Patients With Knee Osteoarthritis.
Lead Sponsor:
University of Jazan
Conditions:
Knee Osteoarthritis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study is designed to investigate whether a hands-on therapy called Mobilization with Movement (MWM) can reduce pain and inflammation in individuals with knee osteoarthritis (OA). The investigator...
Eligibility Criteria
Inclusion
- Clinical diagnosis of unilateral or bilateral knee osteoarthritis (OA) according to the criteria of the American College of Rheumatology
- Age ≥ 18 years
- Kellgren-Lawrence grade 2 or 3 knee OA
- Pain intensity \> 3 on a visual analogue scale (VAS)
- Body mass index (BMI) between 18.5 and 30 kg/m²
Exclusion
- Knee or lower limb surgery within the last six months.
- Significant joint disorders (e.g., rheumatoid arthritis, gout, or other inflammatory arthritis).
- Recent significant acute infections.
- Contraindications to mobilization with movement.
- Current or recent use systemic glucocorticoids, intra-articular glucocorticoid injections or intra-articular hyaluronic acid injections.
Key Trial Info
Start Date :
September 20 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 20 2026
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT07166068
Start Date
September 20 2025
End Date
April 20 2026
Last Update
December 9 2025
Active Locations (1)
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1
Jazan University Hospital
Jizan, Jazan Region, Saudi Arabia, 82722