Status:

NOT_YET_RECRUITING

Predictive Model for Multidrug Resistance in Patients Admitted to the Emergency Department With Sepsis

Lead Sponsor:

Hospital Italiano de Buenos Aires

Conditions:

Sepsis

Septic Shock

Eligibility:

All Genders

18+ years

Brief Summary

Introduction: Timely and accurate antibiotic administration in emergency department (ED) patients with sepsis or septic shock is vital, given mortality rates of 20% and over 40%, respectively. In high...

Detailed Description

Introduction: Timely and accurate antibiotic administration in emergency department (ED) patients with sepsis or septic shock is vital, given mortality rates of 20% and over 40%, respectively. In hig...

Eligibility Criteria

Inclusion

  • Inclusion Criteria
  • Adults aged 18 years or older.
  • Attended at the Adult Emergency Department of Hospital Italiano de Buenos Aires during the periods:
  • January 1, 2017 - March 20, 2020, or
  • May 1, 2022 - August 10, 2025.
  • Sepsis or septic shock at presentation and at least 48 hours of observation or hospital admission.
  • Bacterial cultures obtained during the initial evaluation.
  • Exclusion Criteria
  • No indication for antibiotic therapy within the first 48 hours of hospital admission.
  • No bacterial cultures performed within the first 48 hours of hospital admission.
  • SARS-CoV-2 infection diagnosed within the first 72 hours of hospital admission.

Exclusion

    Key Trial Info

    Start Date :

    October 15 2025

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    October 31 2025

    Estimated Enrollment :

    10000 Patients enrolled

    Trial Details

    Trial ID

    NCT07167173

    Start Date

    October 15 2025

    End Date

    October 31 2025

    Last Update

    September 11 2025

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