Status:

RECRUITING

Carcinogen and Toxicant Exposure Among Young Adults Who Co-Use E-cigarettes and Cannabis (Co-Tox Study)

Lead Sponsor:

Roswell Park Cancer Institute

Conditions:

Cigarette Smoking-Related Carcinoma

E-Cig Use

Eligibility:

All Genders

18-25 years

Brief Summary

This study evaluates the amount of nicotine, cannabis, and toxicants linked to the use of nicotine e-cigarette and/or cannabis products in the blood and urine of young adult users as well as the canna...

Detailed Description

PRIMARY OBJECTIVE: I. To evaluate differences in self-reported nicotine and cannabis use behaviors and biomarkers of exposure to toxicants and carcinogens by product use status, to generate effect si...

Eligibility Criteria

Inclusion

  • Young adult (18-25 years old).
  • Ability to read and write in English.
  • Participants must fall into one of the following groups (based on self-report):
  • Predominant e-cigarette consumer: defined as using nicotine-containing e-cigarettes daily for the past six months but not having used other nicotine containing products more than weekly or cannabis products for the past month.
  • Predominant cannabis consumer: defined as using cannabis at least 3x/week for the past six months in any form, including smoking, vaping, and oral use, with no more than weekly use of any nicotine or tobacco products.
  • E-cigarette-cannabis co-consumers: defined as daily use of nicotine e-cigarettes and use of cannabis at least 3x/week, including smoking, vaping, and oral use, for at least the past six months, with no use of other nicotine containing products more than weekly.
  • No self-reported diagnosis of kidney disease (current, or within the past year prior to the study visit).
  • Participants must understand the voluntary nature of this study and sign a written informed consent form before proceeding with study activities.

Exclusion

  • Individuals under the age of 18 or over the age of 25.
  • Currently pregnant or breastfeeding (female participants).
  • Unwilling or unable to follow protocol requirements

Key Trial Info

Start Date :

April 3 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 1 2028

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT07167225

Start Date

April 3 2025

End Date

September 1 2028

Last Update

October 3 2025

Active Locations (1)

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1

Roswell Park Comprehensive Cancer Center

Buffalo, New York, United States, 14263