Status:

NOT_YET_RECRUITING

Exercise Rehabilitation for Cardiorenal Syndrome in HFrEF Patients

Lead Sponsor:

Haiyan Pan

Conditions:

Cardiorenal Syndrome

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

This study aims to investigate the efficacy and safety of exercise rehabilitation in patients with cardiorenal syndrome (CRS). Building on previous research demonstrating that exercise rehabilitation...

Detailed Description

This study is designed to evaluate the efficacy and safety of home-based exercise rehabilitation as an adjuvant intervention for patients with Cardiorenal Syndrome (CRS) complicated by Chronic Heart F...

Eligibility Criteria

Inclusion

  • Patients with chronically stable HFrEF complicated by kidney dysfunction (eGFR \< 90 mL/min/1.73m²)
  • NYHA class II-III
  • Low risk in exercise risk assessment
  • Aged 18-75 years

Exclusion

  • Uncontrolled hypertension
  • Severe arrhythmias (including frequent ventricular premature contractions, ventricular tachycardia, rapid atrial fibrillation, sick sinus syndrome, and second-degree or higher atrioventricular block)
  • Obstructive hypertrophic cardiomyopathy
  • Moderate to severe stenotic valvular heart disease
  • Deep vein thrombosis or pulmonary embolism
  • History of syncope
  • Severe anemia
  • Abnormal thyroid function
  • Severe pulmonary diseases
  • Mental illnesses
  • Osteoarticular or muscular diseases that impede rehabilitation training

Key Trial Info

Start Date :

September 15 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2027

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT07167368

Start Date

September 15 2025

End Date

December 31 2027

Last Update

September 11 2025

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