Status:

NOT_YET_RECRUITING

Is There a Relationship Between Uric Acid Level and Liver Fibrosis in Obese Patients

Lead Sponsor:

Assiut University

Conditions:

Hyperuricemia

NAFLD (Nonalcoholic Fatty Liver Disease)

Eligibility:

All Genders

18-65 years

Brief Summary

1. Identifying the association between hyperuricemia and NAFLD can lead to early detection and prevention of liver fibrosis in adult obese patients. 2. Understanding the relationship between hyperuric...

Detailed Description

Hyperuricemia is associated with nonalcoholic fatty liver disease (NAFLD), whereas whether the association differed by hyperuricemia onset age remained unclear. This study sought to investigate the as...

Eligibility Criteria

Inclusion

  • Age: Adults (typically 18-65 years old)
  • 2 - Body Mass Index (BMI): Obese patients with a BMI ≥ 30 kg/m²
  • 3- Hyperuricemia : Elevated serum uric acid levels (typically \> 7 mg/dL for men and \> 6 mg/dL for women)

Exclusion

  • excessive alcohol consumption ( \> 20 gm /day in men and 10 in g /day in women )
  • 2- use of steatogenic within the past 6 months
  • 3- positive test for hepatitis B surface antigen and hepatitis B core antibody
  • 4- Drug induced liver injury and autoimmune hepatitis
  • 5 - cirrhosis and other causes of liver disease

Key Trial Info

Start Date :

October 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2026

Estimated Enrollment :

111 Patients enrolled

Trial Details

Trial ID

NCT07168551

Start Date

October 1 2025

End Date

December 1 2026

Last Update

September 15 2025

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