Status:

NOT_YET_RECRUITING

Effects of Wet-Cupping on Polycystic Ovary Syndrome Patients

Lead Sponsor:

Princess Nourah Bint Abdulrahman University

Conditions:

Polycystic Ovarian Syndrome (PCOS)

Eligibility:

FEMALE

20-40 years

Phase:

NA

Brief Summary

The goal of this clinical trial is to evaluate whether wet cupping therapy (Hijama) can improve reproductive and metabolic outcomes in women diagnosed with Polycystic Ovary Syndrome (PCOS). This study...

Eligibility Criteria

Inclusion

  • Inclusion Criteria
  • Female participants.
  • Aged 20 to 40 years.
  • Diagnosed with Polycystic Ovary Syndrome (PCOS) according to the Rotterdam criteria.
  • Willing to participate in the study and provide informed consent.
  • Not using any of the following in the last month: (Hormonal medications for menstruation, Herbal menstrual remedies or Metformin).
  • Exclusion Criteria
  • Known diagnosis of uncontrolled thyroid dysfunction.
  • Diagnosis of diabetes mellitus.
  • Elevated FSH levels above 20 mIU/mL.
  • Hyperprolactinemia with serum levels above 1000 mIU/L.
  • Pregnant or lactating women.
  • Known coagulation disorders.
  • Anemia with hemoglobin levels less than 10 g/dL.
  • History of undergoing dry cupping, wet cupping, or acupuncture in the past 6 months.
  • History of surgical removal of both ovaries or the uterus.
  • Other causes of hyperandrogenism, including:
  • Late-onset non-classic 21-hydroxylase deficiency (excluded clinically; lab investigation if clinically indicated).
  • Ovarian androgen-secreting tumors.
  • Use of anabolic or androgenic drugs.
  • Cushing's syndrome.
  • Hypothalamic or pituitary disorders causing amenorrhea.
  • Primary ovarian insufficiency.

Exclusion

    Key Trial Info

    Start Date :

    January 1 2026

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 31 2026

    Estimated Enrollment :

    60 Patients enrolled

    Trial Details

    Trial ID

    NCT07169292

    Start Date

    January 1 2026

    End Date

    December 31 2026

    Last Update

    September 11 2025

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    King Abdullah bin Abdulaziz University Hospital

    Riyadh, Central, Saudi Arabia, 13249