Status:

NOT_YET_RECRUITING

Multicentre Longitudinal Study of Bone Mineralisation Characteristics in Marfan Syndrome and Ehlers-Danlos Syndrome

Lead Sponsor:

IRCCS Policlinico S. Donato

Collaborating Sponsors:

Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Conditions:

Marfan Syndrome

Ehlers-Danlos Syndrome (EDS)

Eligibility:

All Genders

Brief Summary

The general objective of this research is to evaluate the characteristics of bone mineralisation in patients with Marfan syndrome or Ehlers-Danlos syndrome on a large case series. In particular we in...

Eligibility Criteria

Inclusion

  • Subjects with Marfan syndrome and Ehlers-Danlos syndrome according to the revised reference criteria belonging to the Cardiovascular genetic center at IRCCS Policlinico San Donato and the Reference Centre for Ehlers-Danlos Syndromes Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico;
  • Adult and paediatric subjects who have performed at least one Bone Mineral Densitometry within the observation period of the study.

Exclusion

  • Presence of prostheses in the spinal column;
  • Presence of prostheses in the coxofemoral joint;
  • Oncological bone diseases reported in history.

Key Trial Info

Start Date :

October 31 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 31 2026

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT07169669

Start Date

October 31 2025

End Date

May 31 2026

Last Update

September 12 2025

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