Status:
NOT_YET_RECRUITING
EIT vs Dynamic Compliance Guided PEEP Titration During Laparoscopic Gynecological Surgery
Lead Sponsor:
Pest County Flór Ferenc Hospital
Collaborating Sponsors:
Kiskunhalas Semmelweis Hospital the Teaching Hospital of the University of Szeged
Semmelweis University
Conditions:
Mechanical Power
Postoperative Pulmonary Complications (PPCs)
Eligibility:
FEMALE
18+ years
Phase:
NA
Brief Summary
The goal of this randomized controlled clinical trial is to compare the pulmonary protective effects of two different positive end-expiratory pressure (PEEP) titrating methods in patients with non-inj...
Detailed Description
The aim of this study is to compare the effects of two different - electrical impedance tomography guided (EIT) versus dynamic pulmonary compliance guided (Cdyn) - positive end-expiratory pressure (PE...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Patient scheduled for elective laparoscopic gynaecological surgery
- Age \> 18 years
- Signed consent to participate in the trial
- Exclusion criteria:
- Age \< 18 years
- American Society of Anesthesiologists (ASA) physical status IV
- History of severe restrictive or chronic obstructive pulmonary disease (COPD, Global Initiative for Chronic Obstructive Lung Disease grades III or IV)
- Uncontrolled bronchial asthma
- Pulmonary metastases
- History of any thoracic surgery
- Need for thoracic drainage before surgery
- Congestive heart failure (NYHA grades III or IV)
- Extreme obesity (BMI\>35 kg m-2)
- Lack of patient's consent
Exclusion
Key Trial Info
Start Date :
October 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 30 2027
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT07170514
Start Date
October 1 2025
End Date
October 30 2027
Last Update
September 12 2025
Active Locations (3)
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1
Semmelweis Hospital Kiskunhalas
Kiskunhalas, Bács-Kiskun county, Hungary, 6400
2
Flór Ferenc Hospital Kistarcsa
Kistarcsa, Pest County, Hungary, 2143
3
Semmelweis University
Budapest, Hungary, 1085