Status:
NOT_YET_RECRUITING
Dynamic Impact of NIV on Diaphragmatic Ultrasound in Patients With Amyotrophic Lateral Sclerosis
Lead Sponsor:
University Hospital, Grenoble
Conditions:
Amyotrophic Lateral Sclerosis (ALS)
Non Invasive Ventilation (NIV)
Eligibility:
All Genders
18+ years
Brief Summary
The goal of this pilot observational study is to learn about the dynamic impact of the non invasive ventilation on the diaphragm in patient with amyotrophic lateral sclerosis. The main question it aim...
Detailed Description
Each diaphragmatic ultrasound assessment will be performed on both the right and left hemidiaphragms, with the patient in a semi-recumbent position at 30°, during a maximal inspiratory effort. The fol...
Eligibility Criteria
Inclusion
- Adult patient (≥18 years old)
- Diagnosis of bulbar or spinal amyotrophic lateral sclerosis (ALS) established by a neurologist
- Indication for non-invasive ventilation (NIV) confirmed by the referring pulmonologist for daytime and/or nocturnal alveolar hypoventilation
Exclusion
- Continuous (24-hour) non-invasive ventilation
- Patient refusal to participate
- Individual under legal guardianship or judicial protection
Key Trial Info
Start Date :
September 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 15 2026
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT07170865
Start Date
September 1 2025
End Date
October 15 2026
Last Update
September 12 2025
Active Locations (1)
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1
CHU Grenoble-Alpes
Grenoble, Isère, France, 38043