Status:
NOT_YET_RECRUITING
Components of Mechanical Power on the Functional Lung in ARDS
Lead Sponsor:
Ramos Mejía Hospital
Collaborating Sponsors:
Universidad de la Republica
Conditions:
Respiratory Distress Syndrome (RDS)
Eligibility:
All Genders
18+ years
Brief Summary
Mechanical power (MP) is a composite variable that integrates static and dynamic respiratory parameters and has been associated with ventilator-induced lung injury (VILI). MP is predominantly delivere...
Detailed Description
In patients with acute respiratory distress syndrome (ARDS) who require mechanical ventilation (MV), each respiratory cycle transfers a quantifiable amount of mechanical energy to the lung. This energ...
Eligibility Criteria
Inclusion
- Patients ≥ 18 years
- Diagnosis of acute respiratory distress syndrome
- Receiving invasive mechanical ventilation (volume control mode) for at least 48 consecutive hours.
Exclusion
- Patients spontaneously breathing
- Patients under non-invasive support therapies
- Patients receiving ventilation through a tracheostomy cannula at any time during the first 48 h
- Patients that receiving pressure-controlled ventilation or any modality other than volume-controlled
- Patients with missing data for calculating mechanical power (MP).
- Patients with chronic pulmonary disease
- Patients with a high risk of death within 3 months for reasons other than ARDS
- Patients having made the decision to withhold life-sustaining treatment.
Key Trial Info
Start Date :
December 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 10 2027
Estimated Enrollment :
184 Patients enrolled
Trial Details
Trial ID
NCT07171632
Start Date
December 1 2025
End Date
March 10 2027
Last Update
December 4 2025
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