Status:
ACTIVE_NOT_RECRUITING
Effect of Ozone Use in Intracanal Irrigation on Oxidative Stress Level in Teeth With Asymptomatic Apical Periodontitis
Lead Sponsor:
KEZBAN MELTEM ÇOLAK
Conditions:
Apical Periodontitis
Oxidative Stress
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
This clinical study aims to investigate the oxidative stress-related effects of ozone irrigation in patients with asymptomatic apical periodontitis undergoing root canal treatment. A total of 60 patie...
Detailed Description
This randomized controlled clinical trial investigates the effect of ozone irrigation on oxidative stress levels in teeth diagnosed with asymptomatic apical periodontitis. Apical periodontitis, charac...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- 1\. Patients must be between 18 and 65 years of age 2. Single-rooted, asymptomatic apical periodontitis with necrotic teeth 3. Teeth with periapical lesion size classified as score 3 or 4 according to the Orstavik classification 4. Periapical Assessment Index (PAI) of 2 or higher 5. Patients with ASA I status
- Exclusion Criteria
- Teeth with multiple roots
- Patients with ASA II or higher
- Pregnant women or those suspected of being pregnant
- Patients with a history of allergies
- Teeth with excessive material loss where a rubber dam cannot be applied
- Teeth with root fractures or an open apex
- Teeth that have previously undergone root canal treatment
- Presence of canal curvature greater than Schilder 25°,
- Patients with generalized periodontitis,
- Presence of a periodontal pocket greater than 3mm in the relevant tooth
Exclusion
Key Trial Info
Start Date :
September 27 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 30 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT07171762
Start Date
September 27 2024
End Date
October 30 2025
Last Update
September 18 2025
Active Locations (1)
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1
ATATURK UNIVERSITY, FACULTY of DENTISTRY, Department of ENDODONTICS
Erzurum, Erzurum, Turkey (Türkiye), 25240