Status:

ACTIVE_NOT_RECRUITING

Evaluation of the Effect of Salivary Melatonin Levels on Postoperative Pain and Sleep Quality Following Endodontic Treatments Performed at Different Days and Times

Lead Sponsor:

Ataturk University

Conditions:

Postoperative Pain After Endodontic Treatment

Eligibility:

All Genders

25-45 years

Phase:

NA

Brief Summary

This clinical study aims to evaluate the effect of salivary melatonin levels on postoperative pain and sleep quality in patients undergoing root canal treatment at different times of the day. Each par...

Detailed Description

Postoperative pain following endodontic treatment is a common clinical problem that adversely affects patients' quality of life. Studies have shown that this pain may not only be associated with local...

Eligibility Criteria

Inclusion

  • Patients aged 25-45 years Patients with two asymptomatic, devital mandibular molars in the same arch No radiographic evidence of periapical lesions or pathological formations in the teeth Patients without systemic diseases (ASA I) Patients who have not used antibiotics, analgesics, or melatonin-containing medications within the last week Patients who have signed the informed consent form

Exclusion

  • Patients with a diagnosis of sleep disorder or those regularly using sleep medications/sedatives Patients with systemic diseases (e.g., hypertension, diabetes, endocrine disorders, etc.) Patients receiving psychiatric treatment Pregnant or breastfeeding patients Patients unable to cooperate during the treatment process Patients with restorative or periodontal complications in their teeth Patients working in a shift system

Key Trial Info

Start Date :

September 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 20 2026

Estimated Enrollment :

45 Patients enrolled

Trial Details

Trial ID

NCT07173699

Start Date

September 1 2025

End Date

July 20 2026

Last Update

September 15 2025

Active Locations (1)

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Atatürk University Faculty of Dentistry, Department of Endodontics

Erzurum, Turkey (Türkiye), 25240