Status:
NOT_YET_RECRUITING
Congenital and Maternal Point of Care Rapid Testing for Syphilis Study, Uganda
Lead Sponsor:
St George's, University of London
Collaborating Sponsors:
Johns Hopkins University
MU-JHU CARE
Conditions:
Syphilis
Syphilis, Congenital
Eligibility:
All Genders
14+ years
Brief Summary
Syphilis is an infection which affects about 1 in 25 pregnant women in Uganda. If the infection is not diagnosed and treated this can be a risk to the mother and unborn baby's health. This study aims ...
Detailed Description
Maternal syphilis is a major cause of poor birth outcomes including congenital syphilis (CS), which may cause miscarriage, stillbirth, or birth defects. In 2016, the global maternal syphilis prevalenc...
Eligibility Criteria
Inclusion
- Mothers delivering at Kawempe National Referral Hospital with a positive syphilis rapid diagnostic test during their current pregnancy.
Exclusion
- Mothers who are unable to give written informed consent.
- Mothers with evidence of neurological symptoms compatible with neurological syphilis.
- Mothers who are aged less than 14 years. Emancipated and mature minors are allowed to consent for research per Ugandan law.11
- Mothers, who in the view of the study team, are unable to adhere to required study procedures
Key Trial Info
Start Date :
September 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT07173764
Start Date
September 1 2025
End Date
December 1 2025
Last Update
September 15 2025
Active Locations (1)
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1
Kawempe National Referral Hospital
Kampala, Uganda