Status:

NOT_YET_RECRUITING

A Study to Better Understand the Biological and Molecular Mechanisms Involved in Glioblastoma Recurrence and Progression

Lead Sponsor:

University Hospital, Bordeaux

Collaborating Sponsors:

University of Bordeaux

Conditions:

Glioblastoma

Eligibility:

All Genders

18+ years

Brief Summary

BORDEAUX-GLIO is a prospective, monocentric study which will describe the molecular, immune and metabolic pathways involved in the progression and relapse of glioblastoma, using blood and tumor sample...

Detailed Description

Glioblastoma is the most common and aggressive primary brain tumor in adults, whose relapse is almost systematic despite surgery, radiation therapy and temozolomide (STUPP protocol). Several clinical ...

Eligibility Criteria

Inclusion

  • Patients of 18 years or older, with highly suspected glioblastoma on neuro-imagery
  • Planned surgical tumor resection,
  • No objection to participate in research
  • Signed genetic consent

Exclusion

  • Patients under guardianship, curatorship or protective supervision
  • Taking immunosuppressants
  • Pregnant or breast-feeding women
  • Patients deprived of their liberty by judicial or administrative decision, or under psychiatric care

Key Trial Info

Start Date :

September 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2030

Estimated Enrollment :

45 Patients enrolled

Trial Details

Trial ID

NCT07173829

Start Date

September 1 2025

End Date

December 1 2030

Last Update

September 15 2025

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