Status:

RECRUITING

QUAD-HF - Prospective Registry of Patients With Incident Heart Failure and Left Ventricular Ejection Fraction <50%

Lead Sponsor:

Mid and South Essex NHS Foundation Trust

Collaborating Sponsors:

Anglia Ruskin University

British Society for Heart Failure

Conditions:

Heart Failure

Eligibility:

All Genders

18+ years

Brief Summary

The QUAD-HF registry is an observational study that would enroll patients in the United Kingdom, who have been newly diagnosed with heart failure and a left ventricular ejection fraction \<50%. We pla...

Detailed Description

Heart failure (HF) is a widespread global health challenge, affecting approximately 1 million individuals in the United Kingdom and the prevalence is predicted to almost double in the next decades due...

Eligibility Criteria

Inclusion

  • Age \>18 years
  • Newly diagnosed Heart Failure with a Left Ventricular Ejection Fraction \<50% (≤12 Weeks prior to enrolment).
  • Able and willing to consent.

Exclusion

  • LVEF 50% or more at time of diagnosis
  • Palliative care
  • Unable or unwilling to give consent

Key Trial Info

Start Date :

October 6 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 1 2031

Estimated Enrollment :

4000 Patients enrolled

Trial Details

Trial ID

NCT07174362

Start Date

October 6 2025

End Date

November 1 2031

Last Update

December 16 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Mid and South Essex NHS Foundation Trust

Basildon, Essex, United Kingdom, SS16 5NL

2

British Heart Foundation Glasgow Cardiovascular Research Centre, Glasgow

Glasgow, United Kingdom