Status:
RECRUITING
Efficacy of Quantum Molecular Resonance in Neuropathic Corneal Pain and Corneal Nerve Regeneration
Lead Sponsor:
Singapore Eye Research Institute
Conditions:
Neuropathic Corneal Pain
Eligibility:
All Genders
21+ years
Phase:
NA
Brief Summary
The goal of this study is to evaluate whether Quantum Molecular Resonance (QMR) treatment can effectively reduce eye pain and stimulate corneal nerve regeneration in patients with neuropathic corneal ...
Detailed Description
Neuropathic corneal pain (NCP) is a severe and challenging condition resulting from dysfunctional corneal nerves, with a range of non-specific symptoms. Patients with NCP often experience burning, ach...
Eligibility Criteria
Inclusion
- Be at least 21 years of age.
- Regardless of gender (Male/Female).
- Regardless of race (Chinese/Malay/Indian/Eurasian/Others).
- Diagnosed with neuropathic corneal pain based on the following criteria: presence of neuropathic ocular symptoms (burning, stinging, photophobia, pain, severe dryness), absent or minimal slit-lamp findings to explain the symptoms and corneal nerve abnormalities as detected by IVCM (decreased corneal length and density, presence of neuromas).
- Willing to receive all eye examinations in this study.
Exclusion
- Pregnant women.
- Participants carrying active implantable devices (e.g., pacemakers and hearing aids).
- Oncologic patients under treatment; patient who underwent ocular surgery in the last month.
- Participants who had ocular infection within 6 months, or active ocular infection or inflammation; any concomitant ocular diseases that could potentially induce ocular pain, such as uveitis.
Key Trial Info
Start Date :
November 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT07174739
Start Date
November 1 2023
End Date
December 31 2026
Last Update
September 19 2025
Active Locations (1)
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1
Singapore National Eye Centre
Singapore, Singapore, S169856