Status:

NOT_YET_RECRUITING

Association Between EIT and CT During PEEP Titration in Patients With Acute Respiratory Failure

Lead Sponsor:

Istituto Clinico Humanitas

Conditions:

Acute Hypoxemic Respiratory Failure

Ventilation, Mechanical

Eligibility:

All Genders

18+ years

Brief Summary

This observational study will analyze data already collected by the investigators as part of their routine clinical practice from patients with acute respiratory failure (ARF) treated with mechanical ...

Eligibility Criteria

Inclusion

  • Adults (≥18 years of age) admitted to our Unit with ARF treated with mechanical ventilation
  • The patient undergoes a lung CT and EIT to guide the setting of PEEP as part of our routine clinical practice

Exclusion

  • The patient cannot undergo a lung CT and/or EIT as judged by the attending physician (for instance, transport to the radiology unit may be considered too risky if the patient is extremely severe, or using EIT may be contraindicated because of the presence of a pacemaker)
  • Pregnancy (as this condition alters the respiratory physiology)

Key Trial Info

Start Date :

December 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2027

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT07175194

Start Date

December 1 2025

End Date

June 1 2027

Last Update

September 19 2025

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