Status:
RECRUITING
SISTER: Sibling Oocyte Insemination With Frozen Sperm From Third Party Donors: Evaluation of Reproductive Techniques
Lead Sponsor:
Shady Grove Fertility Reproductive Science Center
Conditions:
Infertility, Female
Reproductive Techniques, Assisted
Eligibility:
FEMALE
Phase:
NA
Brief Summary
The goal of this clinical trial is to learn whether two different methods of helping eggs and sperm join-intracytoplasmic sperm injection (ICSI) and conventional in vitro fertilization (IVF)-lead to b...
Detailed Description
This is a prospective, randomized sibling-oocyte controlled trial designed to compare fertilization and embryo development outcomes between intracytoplasmic sperm injection (ICSI) and conventional in ...
Eligibility Criteria
Inclusion
- Female patients undergoing IVF with frozen donor sperm at Shady Grove Fertility Center
- Normal ovarian reserve (AMH \> 1 ng/mL, AFC \> 10)
- Absence of male factor infertility
- Post-wash parameters: \>50% motility, \>5mil concentration
- \> 4 oocytes retrieved at time of transvaginal oocyte retrieval
Exclusion
- Donor Sperm with significant male factor infertility (e.g., abnormal sperm concentration, motility, or morphology)
- Any medical condition contraindicating ART
Key Trial Info
Start Date :
September 15 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2026
Estimated Enrollment :
95 Patients enrolled
Trial Details
Trial ID
NCT07175571
Start Date
September 15 2025
End Date
May 1 2026
Last Update
September 16 2025
Active Locations (1)
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1
Shady Grove Fertility Rockville
Rockville, Maryland, United States, 20850