Status:

COMPLETED

Methylprednisolone vs Dexamethasone Interaction With Sugammadex in Pediatric Patients

Lead Sponsor:

Konya City Hospital

Conditions:

Neuromuscular Block, Residual

Pain Management

Eligibility:

All Genders

5-12 years

Phase:

NA

Brief Summary

This randomized controlled trial aims to compare the interaction of methylprednisolone and dexamethasone with sugammadex in pediatric patients undergoing adenoidectomy and/or tonsillectomy. The primar...

Detailed Description

Neuromuscular blocking agents (NMBAs) are widely used in pediatric anesthesia to facilitate tracheal intubation and optimize surgical conditions. However, residual neuromuscular block may increase the...

Eligibility Criteria

Inclusion

  • Children aged 5-12 years
  • American Society of Anesthesiologists (ASA) physical status I-II

Exclusion

  • ASA physical status ≥ III
  • Emergency surgery
  • Known allergy or contraindication to neuromuscular blocking agents, sugammadex, or corticosteroids
  • Chronic or recent systemic corticosteroid use (within the last 3 months)
  • Neuromuscular disorders (e.g., muscular dystrophy, myasthenia gravis)
  • Severe hepatic or renal dysfunction
  • Significant respiratory or cardiac disease
  • Anticipated difficult airway or history of difficult intubation
  • Developmental delay or craniofacial anomalies affecting airway management
  • Refusal of consent

Key Trial Info

Start Date :

September 16 2025

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 20 2025

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT07175623

Start Date

September 16 2025

End Date

December 20 2025

Last Update

December 29 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Konya City Hospital

Konya, Karatay, Turkey (Türkiye), 42050

2

Bezmialem Vakıf Univerisity Dragos Hospital

Istanbul, Turkey (Türkiye)