Status:
NOT_YET_RECRUITING
The Use of Urinary Dickkopf 3 (u DKK3) as a New Biomarker Which Can Identify Patients at High Risk of Renal Allograft Dysfunction, Earlier That the Current Established Tests.
Lead Sponsor:
Guy's and St Thomas' NHS Foundation Trust
Conditions:
Renal Transplant Failure
Eligibility:
All Genders
17-75 years
Brief Summary
Kidney function after a renal transplant is monitored closely, particularly in the first year, as the risk of deterioration in graft function is worrying. Graft dysfunction can lead to chronic kidney ...
Detailed Description
Frequent monitoring of allograft function is crucial in renal transplant recipients, particularly in the first year. The current routine laboratory tests such as creatinine, glomerular filtration rate...
Eligibility Criteria
Inclusion
- kidney transplant recipients only Longitudinal data of graft function including serum creatinine, e GFR over 12 months at specific time-points; baseline (1 week after transplantation), 3, 6 and 12 months
Exclusion
- Combined kidney pancreas transplant patients with missing graft function values including serum creatinine, e GFR at the specific time-points.
Key Trial Info
Start Date :
January 1 2026
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2027
Estimated Enrollment :
258 Patients enrolled
Trial Details
Trial ID
NCT07176806
Start Date
January 1 2026
End Date
January 1 2027
Last Update
September 16 2025
Active Locations (1)
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1
Guy's and St Thomas' Hospital NHS foundation Trust
London, United Kingdom, SE1 7EH