Status:
COMPLETED
ALLOPURINOL AND LISINOPRIL FOR DIABETIC KIDNEY PROTECTION: A COMPARATIVE STUDY IN NORMOURICEMIC TYPE 2 DIABETICS
Lead Sponsor:
Narowal Medical College
Collaborating Sponsors:
King Edward Medical University
Conditions:
Diabetic Kidney Disease (DKD)
Eligibility:
All Genders
35+ years
Phase:
NA
Brief Summary
This randomized controlled trial was conducted at the Department of Medicine and Diabetes of Mayo Hospital/King Edward Medical University, Lahore, over one year. A total of 80 patients with type 2 dia...
Detailed Description
This study is a randomized controlled trial conducted at the Department of Medicine and the Diabetic Clinic of Mayo Hospital/King Edward Medical University, Lahore. The duration of the study was one y...
Eligibility Criteria
Inclusion
- patients with type 2 diabetes mellitus on oral hypoglycemic agents, serum creatinine levels less than 1.1 mg/dL, and serum uric acid levels between 5.5-6.5 mg/dL for males and 5-6 mg/dL for females
Exclusion
- patients with tumor lysis syndrome, chronic kidney disease from other causes (e.g., hypertension, glomerulonephritis, polycystic kidney disease, or hydronephrosis), those on medications that could cause hyperuricemia (such as thiazide diuretics) or those on drugs that may induce proteinuria (e.g., NSAIDs, cyclosporine, penicillamine, or gold). Patients with uric acid levels exceeding 7 mg/dL were also excluded
Key Trial Info
Start Date :
May 14 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 18 2024
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT07177898
Start Date
May 14 2023
End Date
November 18 2024
Last Update
September 17 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
King Edward Medical University
Lahore, Punjab Province, Pakistan, 54000