Status:

ENROLLING_BY_INVITATION

Association of Biomarkers and Gastric Antral Motility Index With Feeding Intolerance in Critically Ill Patients

Lead Sponsor:

The First Hospital of Jilin University

Conditions:

Critically Ill Patients Who Are Not Allowed to Eat Orally But Can Initiate Enteral Nutrition Within 48 Hours of ICU

Eligibility:

All Genders

18+ years

Brief Summary

When the subjects are admitted to the department, the researchers will monitor potential biomarkers of gastrointestinal injury before administering enteral nutrition (a small amount of blood is drawn,...

Eligibility Criteria

Inclusion

  • Age ≥18 years
  • Presence of one or more organ system failures within 24 hours of ICU admission (SOFA score ≥2)
  • Expected ICU stay \>48 hours
  • Inability to take oral nutrition
  • No contraindications to enteral nutrition (EN)

Exclusion

  • Patients who have already received enteral nutrition prior to gastric antral motility measurement or biomarker collection
  • Receiving palliative care with expected death within 48 hours
  • Pregnancy
  • Participation in another clinical trial

Key Trial Info

Start Date :

October 20 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2026

Estimated Enrollment :

160 Patients enrolled

Trial Details

Trial ID

NCT07178626

Start Date

October 20 2025

End Date

December 31 2026

Last Update

January 2 2026

Active Locations (1)

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The First Hospital of Jilin University

Changchun, China