Status:
NOT_YET_RECRUITING
Effect of Breathing Training on Symptoms of Gastroesophageal Reflux Disease
Lead Sponsor:
Changhua Christian Hospital
Conditions:
Incentive Spirometer
Diaphragmatic Breathing
Eligibility:
All Genders
20-80 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to evaluate whether two types of breathing training can improve symptoms of gastroesophageal reflux disease (GERD) in adults. The main research questions are: * Do...
Detailed Description
Gastroesophageal reflux disease (GERD) is a prevalent gastrointestinal disorder resulting from dysfunction of the lower esophageal sphincter (LES) and impaired anti-reflux barrier mechanisms. While pr...
Eligibility Criteria
Inclusion
- Adults aged 20 to 80 years
- Endoscopic finding of reflux esophagitis (LA grade A) with proton pump inhibitor (PPI) use \> 2 months, or 24-hour pH monitoring showing acid exposure time (AET) \> 6%, or endoscopic diagnosis of reflux esophagitis LA grade B or higher
- Willingness to comply with the full training and follow-up protocol
Exclusion
- Pregnant or breastfeeding women
- History of anti-reflux surgery
- Severe cardiopulmonary dysfunction or respiratory disease
- Inability to perform the training exercises or attend follow-up visits
Key Trial Info
Start Date :
September 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2026
Estimated Enrollment :
51 Patients enrolled
Trial Details
Trial ID
NCT07179250
Start Date
September 1 2025
End Date
May 1 2026
Last Update
September 26 2025
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