Status:
NOT_YET_RECRUITING
Gut Decolonisation With Neomycin/Metronidazole or Rifaximin Before Colon Surgery
Lead Sponsor:
Universität Luzern
Conditions:
Surgical Site Infection
Colon Surgery
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The goal of this clinical trial is to find out if a gut cleaning using Rifaximin works as well as the usual treatment with Neomycin and Metronidazole to prevent infections after colon surgery. The stu...
Detailed Description
Surgical site infections (SSIs) are the most frequent infections in patients undergoing colon surgery, leading to considerable morbidity, mortality and increased healthcare costs. As SSIs are often ca...
Eligibility Criteria
Inclusion
- aged ≥ 18 years
- undergoind planned colon surgery
- colon surgery will be included in Swissnoso SSI surveillance
- informed consent
Exclusion
- contraindications and/or intolerance to one of the study compounds
- patients with underlying active infection (wound contamination class IV) at the timepoint of incision
- pregnant women
- unable to follow study protocol
Key Trial Info
Start Date :
June 1 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2029
Estimated Enrollment :
458 Patients enrolled
Trial Details
Trial ID
NCT07180615
Start Date
June 1 2026
End Date
June 30 2029
Last Update
September 18 2025
Active Locations (4)
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1
Kantonsspital Aarau
Aarau, Switzerland, 5001
2
Luzerner Kantonsspital
Lucerne, Switzerland, 6006
3
Kantonsspital St. Gallen
Sankt Gallen, Switzerland, 9007
4
Stadtspital Triemli
Zurich, Switzerland, 8063