Status:
ACTIVE_NOT_RECRUITING
AI-Based Prediction Model for Iliofemoral DVT Thrombolysis
Lead Sponsor:
Rajaie Cardiovascular Medical and Research Center
Conditions:
Deep Vein Thrombosis of the Lower Extremities
Eligibility:
All Genders
18+ years
Brief Summary
This prospective single-arm cohort study aims to develop an AI-powered prediction model for treatment outcomes in patients with acute extensive iliofemoral deep vein thrombosis (IF-DVT) undergoing ste...
Eligibility Criteria
Inclusion
- All consecutive adult (≥18 years) patients with an MRV-based diagnosis of acute IF- DVT
- Symptomatic patients with severe pain and\\or leg swelling more than 5 cm
- Willing to participate in the study
Exclusion
- Previous history of VTE
- Presence of DVT syndrome for more than 21 days
- Terminal systemic disease requiring palliative treatment
- Active bleeding
- History of hemorrhagic stroke
- Major fibrinolytic contraindication
- Any hereditary coagulopathy disorders
- Patients with baseline renal dysfunction with an estimated glomerular filtration rate (eGFR) of \< 60 ml/min/1.73m2 due to Cockroft-Gault formula based on the creatinine level at the time of admission
- Having any underlying condition that makes the patient unsuitable for MRV and/or rheolytic thrombectomy procedure (e.g., allergy to contrast agent, claustrophobia)
- Having any underlying disabling condition that necessitates a prolonged complete bed rest prohibiting early ambulation
- Low-quality MRV imaging or motion artifact (exclusion criteria for the imaging sub-studies)
Key Trial Info
Start Date :
July 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2025
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT07181083
Start Date
July 1 2024
End Date
October 1 2025
Last Update
September 18 2025
Active Locations (1)
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1
Rajaie Cardiovascular Medical and Research Institute
Tehran, Tehran Province, Iran, 1995614331