Status:

RECRUITING

The Effectiveness of Intermittent Fasting, Caloric Restriction and Physical Activity On Metabolic Syndrome

Lead Sponsor:

Universiti Putra Malaysia

Conditions:

Metabolic Syndrome

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

Metabolic syndrome (MetS) is a global health issue defined by a cluster of risk factors-abdominal obesity, elevated blood pressure, high fasting blood sugar, high triglycerides, and low HDL cholestero...

Detailed Description

This study aims to evaluate the effectiveness of interventions involving intermittent fasting, physical activity, and caloric restriction on metabolic syndrome biomarkers, body composition and lifesty...

Eligibility Criteria

Inclusion

  • The inclusion criteria will be adult aged 18 years and above who have three or more of the following five risk factors (Kunduraci \& Ozbek, 2020):
  • Abdominal obesity.
  • Elevated triglycerides.
  • Low HDL cholesterol.
  • Elevated blood pressure.
  • Elevated fasting blood glucose.

Exclusion

  • Being pregnant, lactating women.
  • Diagnosis of cardiac failure or/and severe renal or liver diseases, cancer.
  • Having had bariatric surgery.
  • Physical or mental disability.
  • Neurological or cognitive impairment.
  • Participant with severely impaired vision, hearing, or speech.
  • Following a special diet or having changed their dietary pattern within the previous 12 weeks of the study's start date.
  • Use of insulin or sulphonamide derivative oral antidiabetic drugs.
  • Conditions that will seriously affect weight management such as having had bariatric surgery.

Key Trial Info

Start Date :

April 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 30 2027

Estimated Enrollment :

140 Patients enrolled

Trial Details

Trial ID

NCT07181655

Start Date

April 1 2025

End Date

December 30 2027

Last Update

September 24 2025

Active Locations (1)

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1

Associate Professor Dr. Hazizi Abu Saad

Serdang, Selangor, Malaysia, 43300