Status:
RECRUITING
The Effect of Bifidobacterium Probiotics on Gut Microbiota Changes in Healthy Adults During Short-term Travel Along the Silk Road
Lead Sponsor:
Universiti Sains Malaysia
Collaborating Sponsors:
Shanghai Jiao Tong University School of Medicine
Conditions:
Healthy Adult Volunteer
Eligibility:
All Genders
18-65 years
Phase:
PHASE2
Brief Summary
Journeying along the historic Silk Road exposes travelers to dramatic dietary shifts, unfamiliar microbial environments, and the physical stresses of long-distance travel-all known to disrupt gut heal...
Detailed Description
Journeys along the Silk Road-with their unique dietary shifts, unfamiliar water and food sources, novel microbial exposures, altered sleep patterns, and psychological adjustments-can significantly dis...
Eligibility Criteria
Inclusion
- Generally healthy adults
- Scheduled to undertake a short-term round trip (less than 7 days) to abroad
- Able to complete study procedures
- Willing to take intervention products
Exclusion
- Use of antibiotics, probiotics, hormones, immunosuppressants, biologics or JAK inhibitors within four weeks prior to study
- Chronic or severe systemic diseases (including cardiovascular, hepatic, renal, malignant or psychiatric disorders)
- Uncontrolled parasitic infections
- Long-term use of corticosteroids, growth hormone, vitamin B12, lysine or inositol
- Major surgery within one month
- Allergy to probiotic components
- Other conditions deemed inappropriate by investigators
Key Trial Info
Start Date :
October 16 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT07182500
Start Date
October 16 2025
End Date
December 31 2025
Last Update
December 10 2025
Active Locations (2)
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1
Shanghai Jiao Tong University School of Medicine
Huangpu, Shanghai Municipality, China, 200001
2
Universiti Sains Malaysia
George Town, Pulau Pinang, Malaysia, 11800