Status:
COMPLETED
Radiographic Assessment of Deproteinized Porcine Versus Bovine Bone Mineral in Sinus Augmentation
Lead Sponsor:
Guoli Yang
Collaborating Sponsors:
The Dental Hospital of Zhejiang University School of Medicine
National Natural Science Foundation of China
Conditions:
Sinus Floor Elevation
Sinus Floor Augmentation
Eligibility:
All Genders
18-80 years
Brief Summary
The goal of this retrospective study is to compare the radiographic outcomes of deproteinized porcine bone mineral (DPBM) and deproteinized bovine bone mineral (DBBM) following lateral sinus floor aug...
Eligibility Criteria
Inclusion
- Aged between 18 and 80 years;
- Single or multiple missing teeth in the posterior maxilla with a healing period of at least 3 months;
- Complete baseline data and surgical records;
- Underwent LSFA with simultaneous placement of a single implant, grafted exclusively with either DBBM (Bio-Oss®, 0.25-1.0 mm, Geistlich Pharma AG, Wolhusen, Switzerland) or DPBM (THE Graft®, 0.25-1.0 mm, Purgo Biologics, Seoul, Korea);
- Available CBCT images obtained preoperatively (T0), immediately postoperatively (T1), and at 6 months postoperatively (T2);
- RBH ≤6 mm shown by CBCT at T0 at the edentulous site;
- No systemic disease, untreated periapical pathology or active periodontitis;
- Provision of written informed consent for the implant surgery by the patient or their legal guardian.
Exclusion
- Uncontrolled systemic diseases or any bone-metabolism diseases;
- Pregnancy or lactation;
- Head and neck radiation therapy within the past 5 years;
- acute and chronic inflammation in the maxillary sinus;
- Additional vertical or horizontal bone augmentation procedures besides LSFA;
- Use of graft materials other than the specified DBBM or DPBM, or use of composite grafts;
- Heavy smoking (≥20 cigarettes/day), alcohol abuse, or history of substance abuse;
- Placement of multiple implants in the same grafted site (excluded to avoid within-patient confounding).
Key Trial Info
Start Date :
January 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 1 2025
Estimated Enrollment :
56 Patients enrolled
Trial Details
Trial ID
NCT07182929
Start Date
January 1 2024
End Date
July 1 2025
Last Update
September 24 2025
Active Locations (1)
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1
The Affiliated Hospital, School of Stomatology, Zhejiang University., Hangzhou, Zhejiang 310000
Hangzhou, Zhejiang, China, 310000