Status:
NOT_YET_RECRUITING
Lipoprotein a Assessment and Relation to Ca Score in CAD Patients Using MSCT
Lead Sponsor:
Assiut University
Conditions:
Coronary Artery Disease (CAD)
Eligibility:
All Genders
30-80 years
Brief Summary
The goal of this observational study is to evaluate whether serum Lipoprotein(a) \[Lp(a)\] levels are associated with coronary artery calcium (CAC) score measured by multi-slice computed tomography (M...
Detailed Description
Lipoprotein(a) \[Lp(a)\] is a genetically determined lipoprotein particle structurally similar to LDL, with an additional apolipoprotein(a) component. Elevated Lp(a) levels have been identified as an ...
Eligibility Criteria
Inclusion
- 1-adults aged 40-70
- 2- classified as intermediate cardiovascular risk (10-20% 10 years ASCVD risk)
- 3-undergoing MsCT for suspected coronary artery disease
- 4- ability to provide informed consent
Exclusion
- 1- known CAD or prior revascularization
- 2-history of myocardial infarction or stroke
- 3- statin or PCK9 inhibitor use in the past 3 months
- 4-renal insufficiency (eGFR \< 45ml/min/1.73m2)
- 5-active inflammation or autoimmune disease
Key Trial Info
Start Date :
September 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2026
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT07184034
Start Date
September 1 2025
End Date
October 1 2026
Last Update
September 19 2025
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