Status:
NOT_YET_RECRUITING
Clinical Efficacy of NST With Local Delivery of Ozonated Olive Versus Curcumin Gel in Stage II Grade B Periodontitis.
Lead Sponsor:
Cairo University
Collaborating Sponsors:
MTI University
Conditions:
Periodontitis, Adult
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
The aim of this clinical trial is to evaluate the effectiveness of local delivery ozonated olive gel versus curcumin gel as adjunct to scaling and root planing in the treatment of stage II grade B per...
Detailed Description
Periodontitis is an advanced periodontal disease with a distinctive clinical signs and symptoms as rapid attachment loss and bone destruction The primary treatment approach for periodontitis is mecha...
Eligibility Criteria
Inclusion
- Patients diagnosed with stage II periodontitis defined by having interdental CAL 3-4 mm and presence of pocket depth (PD) ≤ 5 mm, and grade B periodontitis characterized by a moderate rate of disease progression.
- Patients agree to a 3-month follow-up period and provide an informed consent.
Exclusion
- Presence of prosthetic crowns, overhanging restorations and orthodontic treatment.
- Teeth with both endo-perio lesions.
- Antibiotics therapy that has an impact on the clinical signs and symptoms of periodontitis in the previous 3 months.
- Anti-inflammatory drugs in the previous 1 month.
- 6\. History of systemic disease, allergy, cardiovascular diseases, diabetes mellitus, hypertension, bleeding disorders, hyperparathyroidism, and compromised medical conditions, pregnant and lactating females.
Key Trial Info
Start Date :
November 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2026
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT07184268
Start Date
November 1 2025
End Date
March 1 2026
Last Update
September 19 2025
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