Status:
RECRUITING
Clinical Outcome of Intra Articular Injection of Autologous Platelet Rich Plasma in Anterior Cruciate Ligament Injury.
Lead Sponsor:
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Conditions:
Anterior Cruciate Ligament
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
This clinical trial will evaluate the effectiveness of platelet-rich plasma (PRP) injections for patients with anterior cruciate ligament (ACL) injury. ACL injuries commonly cause knee instability, pa...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Patients of both sexes who are older than 18 years and younger than 50 years
- 3 or Less than 3-months history of knee injuries
- ACL injury MRI Grade 1 (Low) and medium Grade 2 (Medium) grade
- ACL injury associated with Grade 1 or 2 Posterior cruciate ligament (PCL) tear and/or Grade 1 or 2 meniscal tear
- The Complete Blood Count (CBC) report shows a hemoglobin \> 10gm/dl and platelet count \>150,000/microliter prior to the procedure
- Capable of comprehending informed consent
- Exclusion criteria:
- Patients who have had intra articular corticosteroid injections in the index knee during the last 12 weeks
- Patients who are taking systemic steroid
- Patients who are younger than 18 and older than 50 years
- Those with a history of platelet disorders or on the therapeutic anticoagulant or anti platelet drugs
- Hemoglobin below 10 gm/dl
- Platelet count \<150000/microliter
- Complete tear of both bundles on MRI
- Grade 3 or more PCL and meniscal tear on MRI
- Previous or concurrent ligament reconstruction in the index knee joint.
- Connective tissue disorders like Marfan Syndrome, Ehler-Danlos Syndrome etc.
- Any inflammatory disease like Rheumatoid Arthritis, spondyloarthritis, gout, pseudogout etc involving the knee joint.
Exclusion
Key Trial Info
Start Date :
August 27 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 26 2026
Estimated Enrollment :
52 Patients enrolled
Trial Details
Trial ID
NCT07185802
Start Date
August 27 2025
End Date
August 26 2026
Last Update
September 22 2025
Active Locations (1)
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1
Bangabandhu Sheikh Mujib Medical University
Dhaka, Bangladesh, 1000