Status:

ACTIVE_NOT_RECRUITING

Autologous Fat Grafting in Upper Limb Burns Scars

Lead Sponsor:

Federal University of São Paulo

Conditions:

Autologous Fat Grafting

Burn

Eligibility:

All Genders

Phase:

NA

Brief Summary

Burn injuries are a complex form of trauma with a high risk of complications. When they affect the upper limbs, patients often develop functional contractures and/or pathological scars that significan...

Detailed Description

Burns represent a serious public health issue and are among the leading causes of trauma-related morbidity worldwide. Involvement of the upper limbs frequently results in long-term complications, incl...

Eligibility Criteria

Inclusion

  • Adults aged 18 years or older
  • Presence of burn scars in the upper limbs (functional contractures and/or pathological scars)
  • Scar area suitable for treatment (≥10 cm²)
  • At least 12 months since the initial burn injury
  • Willingness and ability to comply with study procedures and follow-up visits
  • Signed informed consent form

Exclusion

  • Active local or systemic infection at the time of treatment
  • Uncontrolled chronic diseases (e.g., diabetes mellitus with HbA1c \> 8.0%)
  • Use of systemic corticosteroids or immunosuppressants within 30 days before enrollment
  • Previous surgical or injection treatment of the target scar within the past 6 months
  • Known allergy to lidocaine or any material used in the procedures
  • Coagulopathy or use of anticoagulant therapy
  • Pregnancy or breastfeeding

Key Trial Info

Start Date :

July 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2026

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT07186322

Start Date

July 1 2025

End Date

December 31 2026

Last Update

September 22 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Federal University Of São Paulo

São Paulo, São Paulo, Brazil, 04040030