Status:
NOT_YET_RECRUITING
PeRiOperative Medicine Platform Trial
Lead Sponsor:
Monash University
Collaborating Sponsors:
The Alfred
Conditions:
Surgical Site Infection After Major Surgery
Anaesthesia
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Our specific aims are to investigate whether conservative (≤30%), intermediate (50%), or liberal (80%) inspired oxygen during and immediately after surgery: Aim 1: Reduces surgical site infections (SS...
Detailed Description
www.promptssi.org.au
Eligibility Criteria
Inclusion
- PROMPT -
- Adult patient (≥18 years of age at time of admission)
- Scheduled to undergo a surgical procedure involving a skin incision, with an expected duration of at least 2 hours, and a planned overnight hospital stay of at least 1 night (including, but not limited to, cardiac surgery, orthopedic surgery, obstetric, or gynecological surgery).
- PROMPT -
Exclusion
- ASA physical status 5 (moribund, not expected to survive with or without an operation)
- Inability to provide informed consent
- Previous participation in PROMPT within the prior 30 days.
- DSA 02 - PROMPT -
Key Trial Info
Start Date :
December 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2035
Estimated Enrollment :
7800 Patients enrolled
Trial Details
Trial ID
NCT07186634
Start Date
December 1 2025
End Date
December 1 2035
Last Update
September 25 2025
Active Locations (1)
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1
The Alfred
Melbourne, Victoria, Australia, 3004