Status:
COMPLETED
Free Amino-acid Composition of Peri-implant and Periodontal Conditions
Lead Sponsor:
Istanbul Medipol University Hospital
Collaborating Sponsors:
Lokman Hekim University
Ankara University
Conditions:
Peri-Implant Health
Peri Implant Mucositis
Eligibility:
All Genders
20-65 years
Brief Summary
Peri-implant diseases, encompassing peri-implant mucositis and peri-implantitis, are biologically driven inflammatory conditions that threaten the long-term success of dental implants. The microbial s...
Detailed Description
The study included one-hundred and thirty-two patients who applied to the Department of Periodontology at Istanbul Medipol University, Faculty of Dentistry. Four of the one-hundred and thirty-two pati...
Eligibility Criteria
Inclusion
- be between 18 and 65 years of age
- have a minimum of 20 natural teeth, excluding third molars (for non-implant-treated groups)
- be edentulous patients treated with implants loaded at least 1 year prior (for implant-treated groups)
- be in a systemically healthy condition.
Exclusion
- current tobacco use
- chronic use of any systemic medication
- use of antibiotics, anti-inflammatory drugs (including corticosteroids and NSAIDs), immunosuppressants, beta-blockers, calcium channel blockers, anticoagulants, or hormonal contraceptives within the 3 months prior to the study
- receipt of periodontal therapy within the past 6 months
- pregnancy or breastfeeding
- presence of orthodontic appliances a DMFT index (Decayed, Missing, and Filled Teeth per tooth) greater than 2
Key Trial Info
Start Date :
August 2 2024
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 20 2025
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT07187323
Start Date
August 2 2024
End Date
August 20 2025
Last Update
September 23 2025
Active Locations (1)
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1
Istanbul Medipol University, School of Dentistry
Istanbul, Istanbul, Turkey (Türkiye), 34083