Status:
COMPLETED
Comparative Outcomes of Ulcerative Colitis Patients With Mayo Endoscopic Score 1 and Histologic Activity Versus Mayo Endoscopic Score 2
Lead Sponsor:
IRCCS San Raffaele
Conditions:
Ulcerative Colitis (UC)
Eligibility:
All Genders
18+ years
Brief Summary
This retrospective study examines patients with ulcerative colitis who initiated advanced therapy for their disease. In clinical practice, patients with only mild inflammation on endoscopy (Mayo Endos...
Eligibility Criteria
Inclusion
- Confirmed diagnosis of UC (by routine clinical, radiographic, endoscopic and pathologic criteria);
- Patients starting a new advanced treatment for UC (either biologic agents or small molecules);
- Patients with endoscopic MES of 1 or 2 at the endoscopic reassessment (conducted after 12 ± 3 months following the initiation of advanced therapy)
Exclusion
- Patients with unclassified colitis or Crohn's disease;
- Previous colonic surgery (eg. Pouch);
- Patients for whom biopsies were not obtained at the time of endoscopic reassessment (conducted after 12 months following the initiation of advanced therapy);
Key Trial Info
Start Date :
September 1 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2025
Estimated Enrollment :
159 Patients enrolled
Trial Details
Trial ID
NCT07188727
Start Date
September 1 2019
End Date
May 1 2025
Last Update
September 23 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
IRCCS San Raffaele Hospital
Milan, MI, Italy, 20132