Status:
NOT_YET_RECRUITING
The Effect of rTMS Over the SMA on Gait Performance in Parkinson's Disease
Lead Sponsor:
The Hong Kong Polytechnic University
Conditions:
PARKINSON DISEASE (Disorder)
Eligibility:
All Genders
18-89 years
Phase:
NA
Brief Summary
This study aims to investigate the effects of high-frequency and low-frequency repetitive transcranial magnetic stimulation (rTMS) over the supplementary motor area (SMA) on gait performance, especial...
Detailed Description
The goal of this clinical trial is to investigate the effects of high-frequency and low-frequency rTMS over the SMA on gait performance, especially gait initiation, in individuals with PD. The primary...
Eligibility Criteria
Inclusion
- diagnosed with PD according to thecriteria set by Movement Disorder Committee,
- with Hoehn and Yahr stages II-III, which are recognized as representing mild to moderate disease severity,
- have self-reported difficulty in gait initiation, assessed by item 5 of the freezing of gait questionnaire (FOGQ),
- have used a dopaminergic medication dose in the last month,
- a minimum score of 23 of 30 points on the Montreal Cognitive Assessment (MoCA).
Exclusion
- patients with unstable medical conditions,
- unable to provide informed consent,
- other neurological conditions including stroke,
- contraindications for TMS,
- experienced deep brain stimulation treatment,
- no recordable motor evoked potentials (MEPs) with TMS.
Key Trial Info
Start Date :
January 6 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 30 2027
Estimated Enrollment :
81 Patients enrolled
Trial Details
Trial ID
NCT07190235
Start Date
January 6 2026
End Date
April 30 2027
Last Update
January 2 2026
Active Locations (1)
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1
The Hong Kong Polytechnic University
Kowloon, Hong Kong, 000000