Status:

RECRUITING

Head and Neck Cancer Omics/Integrated Precision Medicine (HOPE)

Lead Sponsor:

Samsung Medical Center

Conditions:

Head and Neck Cancer

Eligibility:

All Genders

20+ years

Brief Summary

Study Background and Rationale Head and neck cancer (HNC) is the sixth leading cause of cancer-related death, with over 650,000 new cases diagnosed worldwide each year. About 60% of patients are diagn...

Detailed Description

1. Background and Rationale 1.1 Need for Personalized Precision Medicine in Head and Neck Cancer Head and neck cancer (HNC) ranks as the sixth leading cause of cancer-related death, with over 650,000 ...

Eligibility Criteria

Inclusion

  • Adults aged 20 years or older
  • Histologically confirmed head and neck cancer (including cancers of the oral cavity, pharynx, larynx, nasal cavity, salivary glands, and other head and neck sites) Patients diagnosed at outside institutions but pathologically confirmed as head and neck cancer at Samsung Medical Center are also eligible.)
  • Patients with similar histologic types (including squamous cell carcinoma, undifferentiated carcinoma, poorly differentiated carcinoma, nonkeratinizing carcinoma, and adenocarcinoma), as well as cancers of unknown primary, salivary gland cancers, head and neck malignant melanoma, sarcomas, and other malignancies are eligible.
  • Diagnosed with head and neckk cancer and scheduled to receive, or previously received, appropriate treatment (radiation therapy, cytotoxic chemotherapy, immune checkpoint inhibitors, or surgery).
  • Ability to understand the purpose of the study and willingness to sign informed consent.

Exclusion

  • Any other condition that, in the opinion of the investigator, makes the patient unsuitable for study participation.

Key Trial Info

Start Date :

April 25 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 31 2030

Estimated Enrollment :

350 Patients enrolled

Trial Details

Trial ID

NCT07190573

Start Date

April 25 2025

End Date

January 31 2030

Last Update

September 24 2025

Active Locations (1)

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Samsung Medical Center

Seoul, Seoul, South Korea, 06351