Status:
NOT_YET_RECRUITING
Efficacy of Propofol Combination With Either Ketamine, Dexmedetomidine or Midazolam for Sedation During Upper Gastrointestinal Endoscopic Procedures
Lead Sponsor:
Ain Shams University
Conditions:
Upper Gastrointestinal Endoscopy
Anesthesia
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
The investigators are comparing the efficacy of three different sedative agents in gastrointestinal endoscopic procedures.
Detailed Description
The investigators aim to compare the efficacy of ketamine-propofol, dexmedetomidine-propofol, and midazolam-propofol combinations as procedural sedative agents for adult patients undergoing elective u...
Eligibility Criteria
Inclusion
- Both male and female patients aged between 18 and 65 years
- Patients who are scheduled for elective upper gastrointestinal endoscopic procedures with sedation
- Patients who are classified as ASA (American Society of Anesthesiologists) I and II
Exclusion
- Patient's refusal to participate
- Respiratory compromise as patients with respiratory failure or with active chest conditions, e.g., bronchial asthma or pneumonia
- Cardiovascular compromise including heart failure and shocked patients
- Severe uncontrolled hematemesis with shock or risk of aspiration.
- Patients who are allergic or have any contraindications to any of the used drugs.
- Patients who have a chronic neuropsychiatric disorder or are on a neuropsychiatric drug.
- Patients on long-term sedative medication have a history of drug or alcohol abuse.
- Pregnancy and lactation
Key Trial Info
Start Date :
December 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2026
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT07190612
Start Date
December 1 2025
End Date
March 1 2026
Last Update
September 24 2025
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