Status:
NOT_YET_RECRUITING
How do Patients With Amnesia Acquire New Knowledge?
Lead Sponsor:
University Hospital, Toulouse
Collaborating Sponsors:
National Research Agency, France
Conditions:
Amnesia
Memory Disorder
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
THE STUDY AIMS to constitute the largest group of patients with major memory impairment resulting from various etiology and specific lesions of the medial temporal lobe (MTL) and use a combined psycho...
Detailed Description
The preservation of learning abilities is an essential aspect in the implementation of cognitive rehabilitation programs for patients with an amnesic syndrome. Particularly disabled on a daily basis, ...
Eligibility Criteria
Inclusion
- Patients aged between 18 and 70 years
- Living in France since less than 20 years, being able to understand the French language, and have basic cultural knowledge as evaluated in classical clinical consultation
- Written agreement to participate in the study
- Intellectual capacities compatible with the cognitive tasks and signing of consent
- Affiliation to the French social security system
- For patients: bilateral brain lesion of the medial temporal lobe or the extended hippocampal system
Exclusion
- Subjects under the age of 18 or over 70
- Contraindications for MRI (examples: wearers of a pacemaker or cardiac defibrillator, implanted equipment activated by an electrical, magnetic or mechanical system, wearers of haemostatic clips for intracerebral aneurysms or carotid arteries, wearers of orthopedic implants, claustrophobic)
- Refusal to be informed of an anomaly detected during the MRI
Key Trial Info
Start Date :
January 1 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 31 2030
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT07191197
Start Date
January 1 2026
End Date
January 31 2030
Last Update
December 16 2025
Active Locations (2)
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1
University Hospital of Caen
Caen, France
2
University Hospital of Toulouse
Toulouse, France