Status:

RECRUITING

Intervention Effect of Temporal Interference Stimulation (TIS) on Depressive Disorder

Lead Sponsor:

The Second Hospital of Anhui Medical University

Conditions:

Depressive Disorder

Temporal Interference Stimulation

Eligibility:

All Genders

12-60 years

Phase:

NA

Brief Summary

To investigate the effect of Temporal Interference Stimulation (TIS) on associative memory (AM) in patients with depressive disorder

Detailed Description

Depression group: thirty patients with depressive disorder diagnosed by DSM-5 were recruited from the Second Affiliated Hospital of Anhui Medical University. All participants underwent a structured in...

Eligibility Criteria

Inclusion

  • the patients were diagnosed by more than 2 psychiatrists and met the diagnostic criteria of DSM-5 for depression, and HAMD\>17, BSS\>6, PHQ-15\>5.
  • the age ranged from 18 to 65 years old, and the length of education was more than 5 years.
  • the visual acuity or corrected visual acuity is normal, right-handed, can cooperate with the completion of various experimental tests.

Exclusion

  • accompanied by severe somatic diseases, such as severe heart, liver, renal insufficiency and so on.
  • accompanied by other neurological diseases, such as stroke, epilepsy and so on. pregnant and lactating women.
  • accompanied by other mental disorders, such as drug abuse, schizophrenia, schizophrenic affective

Key Trial Info

Start Date :

September 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2026

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT07191392

Start Date

September 1 2025

End Date

February 1 2026

Last Update

December 23 2025

Active Locations (1)

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Anhui Medical University

Hefei, Anhui, China