Status:

COMPLETED

Effects of Different Fluid Transfusion Regimens On Glycocalyx In Patients Undergoing Thoracic Surgery.

Lead Sponsor:

Kocaeli Derince Education and Research Hospital

Conditions:

Hypervolemia

Hypovolemia

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

Introduction: Endothelial Glycocalyx (EG) composing of proteoglycans heparan sulfate (HS), syndecan, and plasma proteins forms a physiologically active surface layer on the vascular endothelium, regul...

Detailed Description

This prospective, randomized-controlled study was conducted between August 15, 2021, and December 15, 2021, at a University Hospital. Local ethics committee approval (protocol no: 2019/514/154/10) was...

Eligibility Criteria

Inclusion

  • . Being 18-65 years old and in the American Society of Anaesthesiologists (ASA) I-III risk group.

Exclusion

  • Having heart failure
  • Having a previously known vascular disease

Key Trial Info

Start Date :

August 15 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 30 2025

Estimated Enrollment :

41 Patients enrolled

Trial Details

Trial ID

NCT07192523

Start Date

August 15 2021

End Date

August 30 2025

Last Update

January 5 2026

Active Locations (1)

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1

Kartal Dr Lutfi Kirdar City Hospital

Istanbul, Kartal, Turkey (Türkiye), 34000