Status:

NOT_YET_RECRUITING

Effect of Physical Training in Individuals With Hypokalemic and Hyperkalemic Periodic Paralysis

Lead Sponsor:

Rigshospitalet, Denmark

Conditions:

Hypokalemic Periodic Paralysis

Hyperkalemic Periodic Paralysis

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This study wishes to investigate the effects of strength exercise in patients with either HypoPP or HyperPP. The investigators wishes to include participants already diagnosed with either HypoPP or H...

Eligibility Criteria

Inclusion

  • Patients with genetic verified HypoPP or HyperPP
  • Age minimum 18 years
  • Able to walk a minimum of 10 meters independently with or without assistive devices and be able to stand from a chair without using hands

Exclusion

  • Other significant cause of muscle weakness
  • Heart or lung disease which, in the investigator's opinion, makes participation in the study training inadvisable
  • Exclusion from muscle biopsy
  • Anticoagulant treatment
  • Impaired blood clotting due to disease
  • Exclusion from MRI scanning due to:
  • Metal implants in the body that contraindicate MRI scanning or are positioned such that the scan quality is significantly affected
  • Claustrophobia
  • Pregnancy

Key Trial Info

Start Date :

October 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2026

Estimated Enrollment :

36 Patients enrolled

Trial Details

Trial ID

NCT07194174

Start Date

October 1 2025

End Date

December 1 2026

Last Update

September 26 2025

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